Wang Yuxi,Female, born in March 1993, native of Shenyang, Liaoning Province. Associate Researcher. Her research focuses on the resource exploration and utilization of edible and medicinal fungi, encompassing the discovery, identification, synthesis, and pharmacological mechanisms of bioactive natural lead compounds. She has conducted systematic chemical investigations on Ganoderma lucidum, Sanghuangporus vaninii (Huaier), Cordyceps militaris, and related species, resulting in the isolation and structural elucidation of over 400 compounds, including more than 90 novel entities, establishing a solid foundation for the development and utilization of wild edible and medicinal fungal resources. Dr. Wang has published 19 SCI papers in international journals such as Journal of Agricultural and Food Chemistry and Phytochemistry, among which 10 are as first or corresponding author, and has been granted 7 authorized patents.

2015.09-2020.06，Ph.D. degree in Natural Product Chemistry from Shenyang Pharmaceutical University, Shenyang, Liaoning Province, China. 2011.09-2015.06，Bachelor's degree in Traditional Chinese Pharmacy from Shenyang Pharmaceutical University, Shenyang, Liaoning Province, China.

2023–present Associate Researcher of the Institute of Applied Ecology, Chinese Academy of Sciences, Shenyang, China 2020.09-2023.05, Postdoctoral Researcher of the Institute of Applied Ecology, Chinese Academy of Sciences, Shenyang, China

Edible and medicinal fungi；Material basis of pharmacological efficacy；Resource exploration and utilization

1. 2022–2024, National Natural Science Foundation of China: "Mining of Secondary Metabolites from Chinese Ganoderma Species Based on Molecular Networking and Construction of Their Species-Metabolite Correspondence", Principal Investigator 2. 2022–2023, China Postdoctoral Science Foundation (General Program): "Targeted Discovery and Biosynthesis of Biphenyl Ether-derived Anti-drug-resistant Bacterial Lead Compounds from Ganoderma angustisporum", Principal Investigator 3. 2023–2026, Institute-level Project, Shenyang Institute of Applied Ecology, Chinese Academy of Sciences: "'Lvye Outstanding Young Scientist Program'", Principal Investigator

1、Yu-Xi Wang, Zhi-Yong Xu, Shu-Yan Qin, Ning-Ning Du, Guo-Dong Yao, Bin Lin, Xiao-Xiao Huang*, Shao-Jiang Song*. Novel Bisamide Alkaloids Enantiomers from Pepper Roots (Piper nigrum L.) with Acetylcholinesterase Inhibitory and Anti-Neuroinflammatory Effects [J]. Journal of Agricultural and Food Chemistry, 2022, 70(49): 15487-15498. 2、Yu-Xi Wang, Feng-Ying Han, Zhi-Kang Duan, Ye Chang, Bin Lin, Xiao-Bo Wang, Xiao-Xiao Huang*, Guo-Dong Yao*, Shao-Jiang Song*. Phenolics from Archidendron clypearia (Jack) I.C.N. protect SH-SY5Y cells against H2O2-induced oxidative stress [J]. Phytochemistry, 2020, 176: 112414. 3、Yu-Xi Wang, Le Zhou, Jie Wang, Bin Lin, Xiao-Bo Wang, Xiao-Xiao Huang*, Shao-Jiang Song*. Enantiomeric lignans with anti-β-amyloid aggregation activity from the twigs and leaves of Pithecellobium clypearia Benth [J]. Bioorganic Chemistry, 2018, 77: 579-585. 4、Yuxi Wang, Jinghui Jia, Qi Wang, Yulian Wei, Haisheng Yuan*. Secondary metabolites from the cultures of medicinal mushroom Vanderbylia robiniophila and their tyrosinase inhibitory activities [J]. Journal of Fungi, 2023, 9(7), 702-714. 5、Yu-Xi Wang, Bin Lin , Le Zhou, Zhi-Yang Yan, Han Zhang, Xiao-Xiao Huang*, Shao-Jiang Song*. Anti-β-amyloid aggregation activity of enantiomeric furolactone-type lignans from Archidendron clypearia (Jack) I.C.N [J]. Natural product research, 2020, 34(4): 456-463. 6、Yu-Xi Wang, Zhi-Kang Duan, Ye Chang, Zhi-Yang Yan, Xiao-Bo Wang, Xiao-Xiao Huang*, Shao-Jiang Song*. Triterpenes from Archidendron clypearia (Jack) I.C.N. with anti-β-amyloid aggregation activity [J]. Natural Product Research, 2021, 35(16): 2789-2792. 7、Yu-Xi Wang, Qiang-Ren, Zhi-Yang Yan, Wei Wang, Lu Zhao, Ming Bai, Xiao-Bo Wang , Xiao-Xiao Huang*, Shao-Jiang Song*. Flavonoids and their derivatives with β-amyloid aggregation inhibitory activity from the leaves and twigs of Pithecellobium clypearia Benth [J]. Bioorganic & Medicinal Chemistry Letters, 2017, 27: 4823-4827. 8、Yu-Xi Wang, Zhi-Kang Duan, Wan-Yi Shi, Ye Chang, Xiao-Xiao Huang*, Shao-Jiang Song*. A new dilignan from the twigs and leaves of Archidendron clypearia [J]. Journal of Asian Natural Products Research, 2021, 23(6): 609-614. 9、Yaqin Huo1, Shiyuan Ma1 , Xihan He, Yuxi Wang*, Haisheng Yuan*. Steroids from the mushroom Ganoderma shandongense and their AChE inhibitory activities [J]. Steroids, 2025, 216, 109574. 10、Yuxi Wang, Yaqin Huo, Qi Wang, Yulian Wei, Le Zhou, Haisheng Yuan*. Taxonomy-based molecular networks for discovery of triterpenoids from functional mushroom Ganoderma shandongense and their acetylcholinesterase inhibitory activity [J]. Food Bioscience, 2025, 68, 106740.

1. Yuan Haisheng, WANG Yuxi, Xu Fanru, Huo Yaqin, Wei Yulian, Qin Wenmin. Triterpenoid Compounds and Preparation Method and Application Thereof. Application No.: 2025100814239, Filing Date: January 20, 2025, Publication Date: May 6, 2025, Grant Date: November 21, 2025, Authorization Publication No.: CN119930731B, Patent No.: CN202510081423.9 2. Yuan Haisheng, WANG Yuxi, Wei Yulian, Qin Wenmin. Triterpenoid Compounds from Ganoderma angustisporum and Preparation Method and Application Thereof. Application No.: 202211399082.2, Filing Date: November 9, 2022, Authorization Publication No.: CN115894592B, Grant Date: July 23, 2024, Patent No.: ZL 2022 1 1399082.2 3. Yuan Haisheng, WANG Yuxi, Jia Jinghui, Wei Yulian, Qin Wenmin. Steroid Compounds from Sanghuangporus vaninii and Preparation Method and Application Thereof. Application No.: 202211721250.5, Filing Date: December 31, 2022, Authorization Publication No.: CN116217649B, Grant Date: May 17, 2024, Patent No.: ZL 2022 1 1721250.5 4. Song Shaojiang, Huang Xiaoxiao, WANG Yuxi, Chang Ye. Polyphenol Compounds with Neuroprotective Activity and Preparation Method Thereof. Patent No.: ZL201910778418.8, Grant Date: June 18, 2021 5. Song Shaojiang, Huang Xiaoxiao, Duan Zhikang, WANG Yuxi, Yan Zhiyang. Total Alkaloids from Ailanthus altissima Root Bark and Preparation Method and Application Thereof. Patent No.: ZL201910195770.9, Grant Date: July 9, 2021 6. Song Shaojiang, Huang Xiaoxiao, Duan Zhikang, WANG Yuxi. Triterpenoid Compounds from Archidendron clypearia and Preparation and Application Thereof. Patent No.: ZL201910571795.4, Grant Date: June 1, 2021 7. Song Shaojiang, Huang Xiaoxiao, Duan Zhikang, Ren Qiang, WANG Yuxi. Guaiane Sesquiterpenes and Preparation and Application Thereof. Patent No.: ZL201910288536.0, Grant Date: March 23, 2021